主頁 > 專家解碼 > 長期痛症與抑鬱症 | 腰痛及癌痛易招情緒病！醫生：新式非藥物治療治抑鬱同時減輕痛症

長期痛症與抑鬱症 | 腰痛及癌痛易招情緒病！醫生：新式非藥物治療治抑鬱同時減輕痛症

汪嘉佑

精神科專科醫生

日期: 2022-09-27

根據國際痛症研究學會 (IASP) 的定義，長期痛症指在3個月內持續或重複發作的痛症¹。長期痛症及抑鬱症是影響日常生活功能最多的兩種長期病，其中腰痛及抑鬱症在世界不同地方皆為造成最多疾病負擔 (Disease burden) 的疾病之一²。痛症與抑鬱症兩者互相影響，亦擁有部分共同的成因³。近兩年的研究發現，有約6成的長期痛症患者有抑鬱的徵狀。據澳洲的一項大型前瞻性研究指出，患有長期痛症的抑鬱症患者對抗抑鬱藥的反應會較低³，他們的生活質素也比較差⁴。

References:

Treede, R.-D. et al. Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11). pain 160, 19–27 (2019).
Rice, A. S., Smith, B. H. & Blyth, F. M. Pain and the global burden of disease. Pain 157, 791–796 (2016).
Roughan, W. H. et al. Comorbid chronic pain and depression: Shared risk factors and differential antidepressant effectiveness. Front. Psychiatry 12, 643609 (2021).
Elliott, T. E., Renier, C. M. & Palcher, J. A. Chronic pain, depression, and quality of life: correlations and predictive value of the SF-36. Pain Med. 4, 331–339 (2003).
Caraceni, A. & Portenoy, R. K. An international survey of cancer pain characteristics and syndromes. Pain 82, 263–274 (1999).
Geber, C. et al. Pain in chemotherapy-induced neuropathy–More than neuropathic? PAIN® 154, 2877–2887 (2013).
Bennett, M. I. et al. The IASP classification of chronic pain for ICD-11: chronic cancer-related pain. Pain 160, 38–44 (2019).
Sotelo, J. L., Musselman, D. & Nemeroff, C. The biology of depression in cancer and the relationship between depression and cancer progression. Int. Rev. Psychiatry 26, 16–30 (2014).
Laird, B. J. A., Boyd, A. C., Colvin, L. A. & Fallon, M. T. Are cancer pain and depression interdependent? A systematic review. Psycho-Oncol. Chichester Engl. 18, 459–464 (2009).
IsHak, W. W. et al. Pain and depression: a systematic review. Harv. Rev. Psychiatry 26, 352–363 (2018).
Gatzinsky, K. et al. Repetitive transcranial magnetic stimulation of the primary motor cortex in management of chronic neuropathic pain: a systematic review. Scand. J. Pain 21, 8–21 (2021).
Khoo, E.-L. et al. Comparative evaluation of group-based mindfulness-based stress reduction and cognitive behavioural therapy for the treatment and management of chronic pain: A systematic review and network meta-analysis. Evid. Based Ment. Health 22, 26–35 (2019).