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\/><\/p>\n<p>\u81f3\u65bc\u85e5\u7269\u6cbb\u7642\u65b9\u9762\uff0c\u8377\u723e\u8499\u88dc\u5145\u6cbb\u7642\u662f\u7de9\u89e3\u66f4\u5e74\u671f\u6f6e\u71b1\u76dc\u6c57\u75c7\u72c0\u7684\u5e38\u898b\u9078\u64c7\u3002\u4f55\u91ab\u751f\u6307\u51fa\uff0c\u8377\u723e\u8499\u88dc\u5145\u6cbb\u7642\u9700\u5728\u505c\u7d93\u5f8c10\u5e74\u5167\u621660\u6b72\u524d\u9032\u884c\uff0c\u4e14\u6709\u500b\u4eba\u5065\u5eb7\u72c0\u6cc1\u53ca\u6f5b\u5728\u98a8\u96aa\u7684\u8003\u91cf\uff0c\u4f8b\u5982\u66fe\u60a3\u4e73\u764c\u3001\u6709\u4e73\u764c\u5bb6\u65cf\u75c5\u53f2\u3001\u5df2\u5207\u9664\u5b50\u5bae\u3001\u60a3\u56b4\u91cd\u7684\u8840\u7ba1\u75be\u75c5\u7b49\u7684\u66f4\u5e74\u671f\u5973\u6027\uff0c\u90fd\u672a\u5fc5\u9069\u5408\u63a1\u7528\u8377\u723e\u8499\u7642\u6cd5\uff0c\u5b9c\u5148\u5411\u91ab\u751f\u4e86\u89e3\u6e05\u695a\u3002<\/p>\n<p><strong>\u5feb\u901f\u4e86\u89e3\u975e\u8377\u723e\u8499\u6cbb\u7642\u65b0\u9078\u64c7\uff01<\/strong><\/p>\n<p>\u5e78\u800c\uff0c\u8fd1\u5e74\u66f4\u5e74\u671f\u7684\u975e\u8377\u723e\u8499\u6cbb\u7642\u6709\u65b0\u7a81\u7834\u2014\u2014NK-3\u53d7\u9ad4\u62ee\u6297\u5291\u985e\u85e5\u7269\uff0c\u9069\u5408\u56e0\u66f4\u5e74\u671f\u5f15\u8d77\u4e2d\u5ea6\u81f3\u56b4\u91cd\u6f6e\u71b1\u53ca\u76dc\u6c57\u800c\u5f71\u97ff\u751f\u6d3b\u8cea\u7d20\u7684\u5973\u6027\u4f7f\u7528\u3002<\/p>\n<p>\u8ddf\u8377\u723e\u8499\u88dc\u5145\u6cbb\u7642\u76f8\u6bd4\uff0cNK-3\u53d7\u9ad4\u62ee\u6297\u5291\u4e0d\u6703\u5f71\u97ff\u9ad4\u5167\u6fc0\u7d20\u6c34\u5e73\uff0c\u6545\u4e0d\u6703\u589e\u52a0\u60a3\u4e73\u817a\u764c\u6216\u8840\u6813\u7b49\u98a8\u96aa\u3002\u66f4\u6709\u81e8\u5e8a\u7814\u7a76\u986f\u793a\uff0c\u9019\u985e\u85e5\u7269\u8d77\u6548\u8f03\u5feb\uff0c\u90e8\u5206\u5973\u6027\u5728\u670d\u85e5\u6578\u5929\u5167\u5c31\u80fd\u611f\u53d7\u5230\u6709\u95dc\u75c7\u72c0\u660e\u986f\u6539\u5584<sup>2<\/sup>\u3002<\/p>\n<p>\u4f55\u91ab\u751f\u547c\u7c72\uff0c\u66f4\u5e74\u671f\u5973\u6027\u61c9\u53ca\u65e9\u95dc\u6ce8\u5065\u5eb7\u7ba1\u7406\uff0c\u5fc5\u8981\u6642\u7a4d\u6975\u5c31\u91ab\u8aee\u8a62\uff0c\u8a55\u4f30\u500b\u4eba\u75c7\u72c0\u548c\u98a8\u96aa\uff0c\u6709\u52a9\u5236\u5b9a\u5408\u9069\u7684\u6cbb\u7642\u65b9\u6848\uff0c\u6709\u6548\u7de9\u89e3\u66f4\u5e74\u671f\u4e0d\u9069\uff1b\u4e26\u4e14\u4ea6\u61c9\u8a72\u9075\u7167\u91ab\u56d1\u5b9a\u671f\u8986\u8a3a\u53ca\u8ffd\u8e64\u7528\u85e5\u72c0\u6cc1\u3002<\/p>\n<p>\u53c3\u8003\u8cc7\u6599\uff1a<\/p>\n<ol>\n<li>Avis NE, et al. JAMA Intern Med. 2015;175(4):531\u20139.<\/li>\n<li>Lederman, S., Ottery, F. D., Cano, A., Santoro, N., Shapiro, M., Stute, P., Thurston, R. C., English, M., Franklin, C., Lee, M., &amp; Neal-Perry, G. (2023). Fezolinetant for treatment of moderate-to-severe vasomotor symptoms associated with menopause (SKYLIGHT 1): a phase 3 randomised controlled study.\u00a0<em>Lancet (London, England)<\/em>,\u00a0<em>401<\/em>(10382), 1091\u20131102. https:\/\/doi.org\/10.1016\/S0140-6736(23)00085-5<\/li>\n<\/ol>\n<p><strong>\u7279\u7d04\u8cc7\u8a0a<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u96d6\u7136\u5973\u6027\u8e0f\u5165\u66f4\u5e74\u671f\u662f\u81ea\u7136\u7684\u751f\u7406\u904e\u6e21\u968e\u6bb5\uff0c\u4f46\u4e0d\u5c11\u4eba\u9762\u5c0d\u8eab\u9ad4\u7a2e\u7a2e\u8b8a\u5316\u537b\u4e0d\u61c2\u5f97\u61c9\u5c0d\uff0c\u50cf\u662f\u7761\u89ba\u6642\u5927\u91cf\u51fa\u6c57\uff0c\u53ea\u662f\u66ab\u6642\u73fe\u8c61\uff0c\u5fcd\u904e\u53bb\u5c31\u6703\u597d\uff1f\u574a\u9593\u7d93\u5e38\u8a71\u5973\u6027\u66f4\u5e74\u671f\u6703\u51fa\u73fe\u76dc\u6c57\u60c5\u6cc1\uff0c\u9664\u4e86\u9760\u8377\u723e\u8499\u5c31\u5225\u7121\u4ed6\u6cd5\uff1f\u4eca\u65e5healthyD\u9080\u8acb\u4e86\u5a66\u7522\u79d1\u5c08\u79d1\u4f55\u9756\u91ab\u751f\uff0c\u70ba\u5927\u5bb6\u89e3\u7b54\u95dc\u65bc\u66f4\u5e74\u671f\u5e38\u898b\u5fb5\u72c0\u2500\u2500\u76dc\u6c57\u7684\u7591\u60d1\uff0c\u4e26\u5206\u4eab\u4e86\u975e\u8377\u723e\u8499\u6cbb\u7642\u65b0\u9078\u64c7\uff0c\u5e6b\u52a9\u5973\u58eb\u5011\u66f4\u8f15\u9b06\u5ea6\u904e\u66f4\u5e74\u671f\u3002 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\u4f55\u91ab\u751f\u547c\u7c72\uff0c\u66f4\u5e74\u671f\u5973\u6027\u61c9\u53ca\u65e9\u95dc\u6ce8\u5065\u5eb7\u7ba1\u7406\uff0c\u5fc5\u8981\u6642\u7a4d\u6975\u5c31\u91ab\u8aee\u8a62\uff0c\u8a55\u4f30\u500b\u4eba\u75c7\u72c0\u548c\u98a8\u96aa\uff0c\u6709\u52a9\u5236\u5b9a\u5408\u9069\u7684\u6cbb\u7642\u65b9\u6848\uff0c\u6709\u6548\u7de9\u89e3\u66f4\u5e74\u671f\u4e0d\u9069\uff1b\u4e26\u4e14\u4ea6\u61c9\u8a72\u9075\u7167\u91ab\u56d1\u5b9a\u671f\u8986\u8a3a\u53ca\u8ffd\u8e64\u7528\u85e5\u72c0\u6cc1\u3002 \u53c3\u8003\u8cc7\u6599\uff1a Avis NE, et al. JAMA Intern Med. 2015;175(4):531\u20139. Lederman, S., Ottery, F. D., Cano, A., Santoro, N., Shapiro, M., Stute, P., Thurston, R. C., English, M., Franklin, C., Lee, M., &amp; Neal-Perry, G. (2023). 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\u4f55\u91ab\u751f\u547c\u7c72\uff0c\u66f4\u5e74\u671f\u5973\u6027\u61c9\u53ca\u65e9\u95dc\u6ce8\u5065\u5eb7\u7ba1\u7406\uff0c\u5fc5\u8981\u6642\u7a4d\u6975\u5c31\u91ab\u8aee\u8a62\uff0c\u8a55\u4f30\u500b\u4eba\u75c7\u72c0\u548c\u98a8\u96aa\uff0c\u6709\u52a9\u5236\u5b9a\u5408\u9069\u7684\u6cbb\u7642\u65b9\u6848\uff0c\u6709\u6548\u7de9\u89e3\u66f4\u5e74\u671f\u4e0d\u9069\uff1b\u4e26\u4e14\u4ea6\u61c9\u8a72\u9075\u7167\u91ab\u56d1\u5b9a\u671f\u8986\u8a3a\u53ca\u8ffd\u8e64\u7528\u85e5\u72c0\u6cc1\u3002 \u53c3\u8003\u8cc7\u6599\uff1a Avis NE, et al. JAMA Intern Med. 2015;175(4):531\u20139. Lederman, S., Ottery, F. D., Cano, A., Santoro, N., Shapiro, M., Stute, P., Thurston, R. C., English, M., Franklin, C., Lee, M., &amp; Neal-Perry, G. (2023). 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\u4f55\u91ab\u751f\u547c\u7c72\uff0c\u66f4\u5e74\u671f\u5973\u6027\u61c9\u53ca\u65e9\u95dc\u6ce8\u5065\u5eb7\u7ba1\u7406\uff0c\u5fc5\u8981\u6642\u7a4d\u6975\u5c31\u91ab\u8aee\u8a62\uff0c\u8a55\u4f30\u500b\u4eba\u75c7\u72c0\u548c\u98a8\u96aa\uff0c\u6709\u52a9\u5236\u5b9a\u5408\u9069\u7684\u6cbb\u7642\u65b9\u6848\uff0c\u6709\u6548\u7de9\u89e3\u66f4\u5e74\u671f\u4e0d\u9069\uff1b\u4e26\u4e14\u4ea6\u61c9\u8a72\u9075\u7167\u91ab\u56d1\u5b9a\u671f\u8986\u8a3a\u53ca\u8ffd\u8e64\u7528\u85e5\u72c0\u6cc1\u3002 \u53c3\u8003\u8cc7\u6599\uff1a Avis NE, et al. JAMA Intern Med. 2015;175(4):531\u20139. Lederman, S., Ottery, F. D., Cano, A., Santoro, N., Shapiro, M., Stute, P., Thurston, R. C., English, M., Franklin, C., Lee, M., &amp; Neal-Perry, G. (2023). 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